Frontiers

Molecular Cancer | Integrin-targeted cytotoxin ProAgio reprograms the pancreatic cancer microenvironment and enhances chemotherapy efficacy

Cell | Spatial Proximity between LAG-3 and TCR Guides T Cell Suppression and Mechanisms of Autoimmunity Regulation

Signal Transduction and Targeted Therapy | Targeting BIRC6 rejuvenates hematopoietic stem cell aging and immunosenescence

Nature | PLA2G2D Regulates Anti-Tumor Immunity in Tumor-Draining Lymph Nodes

Journal of Clinical Oncology | Phase Ib Study Results of an EGFR-HER3 Bispecific ADC in Extensive-Stage Small Cell Lung Cancer

Nature | GPCR-TfR1 Targeted Chimeras (GTACs) Achieve Potent Antagonism via Reprogramming Receptor Trafficking and Lysosomal Degradation

Antibodies | B Cells and Tumor Immunometabolism: Emerging Insights into Immune Regulation and Therapeutic Resistance

Nature Communications | Dysfunction of Tertiary Lymphoid Structures in the Muscularis Propria of Gastric Cancer and the Immunosuppressive Mechanism Mediated by PLA2G2A

Theranostics | PEGylated IL2 Combined with Targeted Radiotherapy and Anti-PD-1 Enhances CD8+ T Cell Memory Response in Head and Neck Squamous Cell Carcinoma

Advanced Science | Anti-EGFR Nanobody-Mediated Delivery of RIBOTACs for miR-21 Degradation in Pancreatic Cancer Therapy