Global R&D Pipeline
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IGF1R
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Total number of drugs
133
Phase II and later clinical stages
16.5%
Involving companies
139
Main therapeutic areas
Neoplasms
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Molecule Info
R&D and Market Info
ADC Info
| Drug | Drug Name En | Drug Type | Treatment Field | Mechanism of Action | Originator | Developer | Indication | Highest Development Stage | Highest Development Stage (China) | Approved Countries/Regions | Approved Time | Approved Time (China) | Special Review | ADC Type | ADC Linker | ADC Payload | ADC DAR | Drug Name | Antibody Type | ADC Linking Site | Operation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ScLCDV1-VILP | ScLCDV1-VILP | Synthetic peptide | Neoplasms Endocrinology and Metabolic Disease | IGF-1R antagonists | Harvard Medical School | Harvard Medical School | Preclinical | - | - | - | - | - | - | - | - | - | ScLCDV1-VILP | - | - | detail > | |
| YDK-03 | YDK-03 | Growth factors | Nervous System Diseases Otorhinolaryngologic Diseases Other Diseases | IGF-1R agonists | Zhejiang Younuojin Bioengineering Co., Ltd. | Zhejiang Younuojin Bioengineering Co., Ltd. | Preclinical | Preclinical | - | - | - | - | - | - | - | - | YDK-03 | - | - | detail > | |
| Insulin Like Growth Factor1 (SarcoMed) | Insulin Like Growth Factor1 (SarcoMed) | Hormone | Nervous System Diseases Congenital Disorders Endocrinology and Metabolic Disease Skin and Musculoskeletal Diseases Other Diseases | IGF-1R modulators | Sarcomed AB | Sarcomed AB | Preclinical | - | - | - | - | Orphan Drug（United States） | - | - | - | - | Insulin Like Growth Factor1 (SarcoMed) | - | - | detail > | |
| IOC-001 | IOC-001 | ASO | Neoplasms Endocrinology and Metabolic Disease Urogenital Diseases | IGF-1R antagonists | Imvax, Inc. | Imvax, Inc. | Preclinical | - | - | - | - | - | - | - | - | - | IOC-001 | - | - | detail > | |
| MOD-13012 (Opko Biologis) | MOD-13012 (Opko Biologis) | CTP fusion protein | Nervous System Diseases Otorhinolaryngologic Diseases Other Diseases | IGF-1R agonists | OPKO Biologics Ltd. | Prolor Biotech Ltd. | Preclinical | - | - | - | - | - | - | - | - | - | MOD-13012 (Opko Biologis) | - | - | detail > | |
| IMV-001 | IMV-001 | ASO | Neoplasms | IGF-1R antagonists | Imvax, Inc. | Imvax, Inc. | Preclinical | - | - | - | - | - | - | - | - | - | IMV-001 | - | - | detail > | |
| AZD-3463 | AZD-3463 | Small molecule drug | Neoplasms Respiratory Diseases | ALK inhibitors IGF-1R antagonists | AstraZeneca PLC | Japanese Foundation for Cancer Research | Preclinical | - | - | - | - | - | - | - | - | - | AZD-3463 | - | - | detail > | |
| BCG-009 | BCG-009 | Monoclonal antibody | Immune System Diseases Congenital Disorders Endocrinology and Metabolic Disease Eye Diseases | IGF-1R modulators | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. | Phase 1 | Phase 1 | - | - | - | - | - | - | - | - | BCG-009 | - | - | detail > | |
| Insulin-Like Growth Factor 1(Wright State Physicians, Inc.) | Insulin-Like Growth Factor 1(Wright State Physicians, Inc.) | Growth factors | Skin and Musculoskeletal Diseases Other Diseases | IGF-1R agonists | Wright State Physicians, Inc. | Wright State Physicians, Inc. | Phase 1 | - | - | - | - | - | - | - | - | - | Insulin-Like Growth Factor 1(Wright State Physicians, Inc.) | - | - | detail > | |
| VB-421 | VB-421 | Monoclonal antibody | Immune System Diseases Congenital Disorders Endocrinology and Metabolic Disease Eye Diseases | IGF-1R antagonists | Pierre Fabre SA | ValenzaBio, Inc. | Phase 1 | - | - | - | - | - | - | - | - | - | VB-421 | - | - | detail > |
Total 133 data
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