Global R&D Pipeline
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Total number of drugs
31
Phase II and later clinical stages
16.1%
Involving companies
55
Main therapeutic areas
Other Diseases
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Molecule Info
R&D and Market Info
ADC Info
| Drug | Drug Name En | Drug Type | Treatment Field | Mechanism of Action | Originator | Developer | Indication | Highest Development Stage | Highest Development Stage (China) | Approved Countries/Regions | Approved Time | Approved Time (China) | Special Review | ADC Type | ADC Linker | ADC Payload | ADC DAR | Drug Name | Antibody Type | ADC Linking Site | Operation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LAE-123 | LAE-123 | Antibody | Nervous System Diseases Other Diseases | ACVR2A inhibitors ACVR2B inhibitors | Laekna Therapeutics (Shanghai) Co., Ltd. | Laekna Therapeutics (Shanghai) Co., Ltd. | Discovery | Discovery | - | - | - | - | - | - | - | - | LAE-123 | - | - | detail > | |
| SPCD-4-79 | SPCD-4-79 | Small molecule drug | Endocrinology and Metabolic Disease | ACVR2A inhibitors ACVR2B inhibitors | East China Normal University Fudan University | Supercede Therapeutics, Inc. | Preclinical | - | - | - | - | - | - | - | - | - | SPCD-4-79 | - | - | detail > | |
| GenSci156 | GenSci156 | Bispecific antibody | Endocrinology and Metabolic Disease | ACVR2A inhibitors ACVR2B inhibitors GIPR modulators | Changchun Genescience Pharmaceuticals Co., Ltd. | Changchun Genescience Pharmaceuticals Co., Ltd. | Preclinical | Preclinical | - | - | - | - | - | - | - | - | GenSci156 | - | - | detail > | |
| ActRII A/B monoclonal antibody (CSPC Pharmaceutical) | ActRII A/B monoclonal antibody (CSPC Pharmaceutical) | Monoclonal antibody | Endocrinology and Metabolic Disease | ACTRII inhibitors | CSPC Pharmaceutical Group Ltd. | CSPC Pharmaceutical Group Ltd. | Preclinical | Preclinical | - | - | - | - | - | - | - | - | ActRII A/B monoclonal antibody (CSPC Pharmaceutical) | - | - | detail > | |
| IMC-004 (ImmuneOnco) | IMC-004 (ImmuneOnco) | Bispecific antibody | Nervous System Diseases Endocrinology and Metabolic Disease Skin and Musculoskeletal Diseases Other Diseases | ACVR2A inhibitors | ImmuneOnco Biopharmaceuticals (Shanghai), Inc. | ImmuneOnco Biopharmaceuticals (Shanghai), Inc. | Preclinical | Preclinical | - | - | - | - | - | - | - | - | IMC-004 (ImmuneOnco) | - | - | detail > | |
| ActRIIB inhibitor (Fudan University) | ActRIIB inhibitor (Fudan University) | Small molecule drug | Other Diseases | ACVR2B inhibitors | Fudan University | Fudan University | Preclinical | Preclinical | - | - | - | - | - | - | - | - | ActRIIB inhibitor (Fudan University) | - | - | detail > | |
| rAAV-based gene therapy (Baker IDI Heart & Diabetes Institute/Monash University/University of Melbourne) | rAAV-based gene therapy (Baker IDI Heart & Diabetes Institute/Monash University/University of Melbourne) | AAV based gene therapy | Other Diseases | ACVR2B inhibitors Gene transference | Baker Heart & Diabetes Institute | Baker Heart & Diabetes Institute Monash University University of Melbourne | Preclinical | - | - | - | - | - | - | - | - | - | rAAV-based gene therapy (Baker IDI Heart & Diabetes Institute/Monash University/University of Melbourne) | - | - | detail > | |
| Pulmonary Arterial Hypertension Treatment (AliveGen) | Pulmonary Arterial Hypertension Treatment (AliveGen) | Fusion protein | Respiratory Diseases Other Diseases | ACVR2B agonists | - | AliveGen USA, Inc. | Preclinical | - | - | - | - | Orphan Drug（United States） | - | - | - | - | Pulmonary Arterial Hypertension Treatment (AliveGen) | - | - | detail > | |
| ACE-2494 | ACE-2494 | Fusion protein | - | ACVR2A inhibitors ACVR2B modulators MSTN inhibitors | Acceleron Pharma, Inc. | - | Pending (in Phase 1) | - | - | - | - | - | - | - | - | - | ACE-2494 | - | - | detail > | |
| ATA M43 | ATA M43 | Bispecific antibody | Nervous System Diseases Other Diseases | ACVR2A inhibitors ACVR2B inhibitors | Amgen, Inc. | - | Pending (in Preclinical) | - | - | - | - | - | - | - | - | - | ATA M43 | - | - | detail > |
Total 31 data
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