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Global R&D Pipeline
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Hot Targets:
CD19
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Total number of drugs
934
Phase II and later clinical stages
6.4%
Involving companies
819
Main therapeutic areas
Neoplasms
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R&D and Market Info
ADC Info
DrugDrug Name EnDrug TypeTreatment FieldMechanism of ActionOriginatorDeveloperIndicationHighest Development StageHighest Development Stage (China)Approved Countries/RegionsApproved TimeApproved Time (China)Special ReviewADC TypeADC LinkerADC PayloadADC DARDrug NameAntibody TypeADC Linking SiteOperation
ALLO-501ALLO-501Universal CAR-TNeoplasms Immune System Diseases Hemic and Lymphatic DiseasesCD19 inhibitorsCellectis SAInstitut de Recherches Intern Servier Cellectis, Inc. Les Laboratoires Servier SAS Allogene Therapeutics, Inc. Cellectis SA Institut Servier de Medecine Translationnelle SARLPhase 2----Advanced Therapy Medicinal Products(European Union)----ALLO-501--
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Cemacabtagene ansegedleucelCemacabtagene ansegedleucelUniversal CAR-TNeoplasms Immune System Diseases Hemic and Lymphatic Diseases Other DiseasesCD19 modulatorsCellectis SAAllogene Therapeutics, Inc. Servier Pharmaceuticals LLCPhase 2----Fast Track(United States) Regenerative Medicine Advanced Therapy(United States)----Cemacabtagene ansegedleucel--
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Anti-CD19 CAR T-cells(KK Women's and Children's Hospital)Anti-CD19 CAR T-cells(KK Women's and Children's Hospital)Universal CAR-T-CD19 inhibitors Immunologic cytotoxicity T lymphocyte replacementsKK Women's & Children's Hospital Pte Ltd.KK Women's & Children's Hospital Pte Ltd. Singapore General Hospital Pte Ltd.Phase 2---------Anti-CD19 CAR T-cells(KK Women's and Children's Hospital)--
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Senl-1904BSenl-1904BAutologous CAR-TNeoplasms Immune System Diseases Hemic and Lymphatic Diseases Other DiseasesCD19 inhibitors Gene transference T lymphocyte replacementsHebei Senlangbio Biotechnology Co., Ltd.Hebei Senlangbio Biotechnology Co., Ltd.Phase 2Phase 2--------Senl-1904B--
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Anti-CD19 CAR-T cell therapy(Bellicum Pharmaceuticals, Inc.)Anti-CD19 CAR-T cell therapy(Bellicum Pharmaceuticals, Inc.)CAR-TNeoplasms Immune System Diseases Hemic and Lymphatic DiseasesCD19 modulatorsBellicum Pharmaceuticals, Inc.Bellicum Pharmaceuticals, Inc.Phase 2---------Anti-CD19 CAR-T cell therapy(Bellicum Pharmaceuticals, Inc.)--
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CC-97540CC-97540Autologous CAR-TImmune System Diseases Skin and Musculoskeletal Diseases Urogenital Diseases Neoplasms Nervous System Diseases Hemic and Lymphatic Diseases Other DiseasesCD19 modulators Immunologic cytotoxicity T lymphocyte replacementsJuno Therapeutics, Inc.Celgene Corp. Bristol Myers Squibb Co. Juno Therapeutics, Inc.Phase 2---------CC-97540--
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Zamtocabtagene autoleucelZamtocabtagene autoleucelAutologous CAR-TNeoplasms Immune System Diseases Infectious Diseases Hemic and Lymphatic Diseases Other Diseases Nervous System Diseases Cardiovascular Diseases Congenital Disorders Skin and Musculoskeletal Diseases Urogenital DiseasesCD19 inhibitors CD20 inhibitors T lymphocyte replacementsMiltenyi Biomedicine GmbHNational Institute For Health & Care Research Miltenyi Biomedicine GmbH Miltenyi Biotec BV & Co. KGPhase 2---------Zamtocabtagene autoleucel--
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KYV-101KYV-101Autologous CAR-TNeoplasms Immune System Diseases Nervous System Diseases Skin and Musculoskeletal Diseases Other Diseases Cardiovascular Diseases Urogenital Diseases Respiratory DiseasesCD19 inhibitors CD28 agonists T lymphocyte replacementsKyverna Therapeutics, Inc.Kyverna Therapeutics, Inc. Hannover Medical SchoolPhase 2/3----Fast Track(United States) Orphan Drug(United States) Regenerative Medicine Advanced Therapy(United States)----KYV-101--
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CD19 CAR-T CELLS(Gaia Science)CD19 CAR-T CELLS(Gaia Science)Autologous CAR-TNeoplasms Immune System Diseases Infectious Diseases Hemic and Lymphatic Diseases Other Diseases Skin and Musculoskeletal DiseasesCD19 inhibitors Gene transferenceGaia Science Pte Ltd.University of Kebangsaan Malaysia Gaia Science Pte Ltd.Phase 2/3---------CD19 CAR-T CELLS(Gaia Science)--
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CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes(City of Hope National Medical Center)CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes(City of Hope National Medical Center)Autologous CAR-TNeoplasms Immune System Diseases Hemic and Lymphatic Diseases Other DiseasesCD19 inhibitors CD28 agonists EGFR modulators Cell replacementsCity of Hope National Medical CenterCity of Hope National Medical CenterPhase 2---------CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes(City of Hope National Medical Center)--
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Total 934 data
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